By Austin Che The savory bacon, lettuce, and tomato sandwich lies temptingly on the table. Salivary glands begin to cause salivation in my mouth and gastrin is released in my stomach. As the sandwich enters the oral cavity, sometimes known as the mouth, the incisors, canines, premolars, and molars quickly tear the sandwich to pieces. By now the anti-bacterial agents in the saliva has assured the complete deadness of the food. Salivary amylase hydrolyzes the polysaccharides into maltose. After playing around with the mush of dead food, my tongue expertly shapes the food into a ball like bolus. After the common sandwich has been transformed into a wonderful bolus, it is pushed into the pharynx, which doesn't seem much different from my throat. While swallowing, the dutiful epiglottis blocks the trachea against the entry of food as the lungs are usually not too fond of bacon, lettuce, and tomato sandwiches. Passing by the epiglottis sentry, the sandwich, now a bolus, inches into the esophagus for its journey onward. Peristalsis, waves of contraction and relaxing of smooth muscles, pushes the hesitant bolus through the cardiac orifice and into the stomach. Inside the stomach, the bolus is immediately hit by the gastric juice that knows no friend. Destroying everything in sight, the gastric juice proves to be a formidable enemy against the toughest bacteria and strongest sandwiches. Pepsin in the gastric juice hydrolyzes proteins, cleaving them into pieces. About every twenty seconds, the bacon in the sandwich is mixed with the lettuce and the tomato until the truly mixed up sandwich advances to the next stage, becoming the acid chyme. The pyloric sphincter squirts piece by piece of the chyme, once a sandwich, to proceed on the longest part of its journey - the dreaded small intestine. Many other cohorts have teamed up with the small intestine to attack what was now only the chyme. The pancreas adds its assortment of hydrolytic enzymes as well as bicarbonate, which offsets the acidity of the no longer sandwich. The liver produces bile which is stored in the gallbladder and released into the small intestines, which aid in the digestion and absorption of fats. With everything being thrown at the poor sandwich within the first twenty-five cm or so of the small intestine, the sandwich cannot but help feel unwanted as everything yearns to break it apart. Within this section of the small intestine, also known as the duodenum, secretin is used to signal the pancreas to release bicarbonate to neutralize the invader. Cholecystokinin is another hormone, causing bile to be released into the small intestine. Enterogastrone is also released, as the fatty sandwich needs more time to digest, peristalsis is slowed down. The commander enterokinase starts the battle by signaling the beginning of the attack. Disaccharidases attack disaccharides such as maltose, sucrose, and lactose. The army also includes trypsin and chymotrypsin which break polypeptides into shorter chains. Carboxypeptidase splits off one amino acid at a time, while its partner aminopeptidase distracts the protein from the opposite direction. Dipeptidases also exist which sit in the intestinal lining digestion the easy fragments consisting of only two or three amino acids. Nucleases hydrolyze DNA and RNA present in food. After bile salts have emulsified fat, lipase hydrolyzes the fat molecules. Past the duodenum, the attack dies down, and what remains of the sandwich limps on to the jejunum and ileum. Many villi and microvilli can be found on the small intestines ushering out what it deems to be worthy. Some nutrients are transported out of the small intestines by diffusion while others are coupled to the active transport of sodium across the membranes. All the nutrients enter the capillaries or lacteals, which converge into the hepatic portal vein, leading to the liver. In the liver is where the prisoners of war are converted to become more useful in their new home. The colon or large intestine takes what remains of the sandwich after it leaves the small intestine. The cecum is located at the junction of the colon and the small intestine. Travelling through the colon, much water is absorbed, combining the no longer recognizable sandwich into feces. Within the colon are many bacteria who can not but be pleased at the tasty sandwich. The cellulose fibers found in parts of the sandwich help move the food along the digestive tract. Soon, the end of the journey will approach. Remaining unwanted wastes are thrown into the rectum, to be released through the anus and back out into the world as something other than a sandwich with bacon, lettuce, and tomatoes. It is truly difficult being a sandwich.